Skip to main content
SalaryTruthBLS DATA

Updated May 2026 · BLS OEWS 2025 reference period

Missouri · COL Index 90

64 Highest Paying Jobs in St. Louis, MO (2026)

The highest-paying job in St. Louis, MO, Missouri is Pediatrician with a median salary of $223,910 as of 2026, based on Bureau of Labor Statistics OEWS data. Across all 64 tracked occupations the average median is $101,234, with 29 occupations paying a six-figure ($100K+) median. St. Louis, MO has a cost-of-living index of 90 (national average = 100), so a $101,234 nominal salary equals $112,482 in average-cost-metro buying power.

The 64 occupations below are ranked by median wage in St. Louis, MO, MO, from BLS OEWS data. St. Louis, MO's cost-of-living index runs 90.0 (national baseline = 100), which shapes the headline-wage interpretation. Top-paying occupations in any U.S. metro typically cluster around physicians, dentists, executives, tech specialists, and licensed professionals. The specific top of the list varies with local industry concentration: tech-heavy metros boost software-engineering ranks, finance-heavy metros boost banking ranks.

Each role on the ranking links to the per-role-and-city page with full percentile distribution (p10 to p90), employment count, and cost-adjusted wage. For workers comparing offers within St. Louis, MO, the percentile data is the most decision-relevant.

$223,910
Top Salary
29
Six-Figure ($100,000+) Jobs
$101,234
Average Median
$112,482
COL-Adjusted Avg

Top 10 Highest-Paying Jobs in St. Louis, MO

Ranked by median (50th percentile) salary. The COL-Adjusted column rebases each nominal salary to St. Louis, MO's cost-of-living index of 90 so you can compare buying power against an average-cost U.S. metro.

#1PediatricianHealthcare

Median $223,910 · 10th–90th $65,700$344,020 · 320 jobs in metro

Pediatricians in St. Louis, MO earn $223,910 median, with top earners (90th percentile) over $344,020. The lower cost of living here means the median translates to $248,789 of buying power versus an average-cost metro — better than the nominal number suggests.

$223,910
median
#2DentistHealthcare

Median $210,430 · 10th–90th $96,300$559,260 · 1,250 jobs in metro

Dentists in St. Louis, MO earn $210,430 median, with top earners (90th percentile) over $559,260. The lower cost of living here means the median translates to $233,811 of buying power versus an average-cost metro — better than the nominal number suggests.

$210,430
median

Median $167,130 · 10th–90th $103,330$217,130 · 6,160 jobs in metro

Computer and Information Systems Managers in St. Louis, MO earn $167,130 median, with top earners (90th percentile) over $217,130. The lower cost of living here means the median translates to $185,700 of buying power versus an average-cost metro — better than the nominal number suggests.

$167,130
median

Median $158,780 · 10th–90th $92,720$304,260 · 7,190 jobs in metro

Financial Managers in St. Louis, MO earn $158,780 median, with top earners (90th percentile) over $304,260. The lower cost of living here means the median translates to $176,422 of buying power versus an average-cost metro — better than the nominal number suggests.

$158,780
median
#5LawyerLegal

Median $142,690 · 10th–90th $67,600$306,650 · 6,100 jobs in metro

Lawyers in St. Louis, MO earn $142,690 median, with top earners (90th percentile) over $306,650. The lower cost of living here means the median translates to $158,544 of buying power versus an average-cost metro — better than the nominal number suggests.

$142,690
median

Median $142,660 · 10th–90th $79,000$246,240 · 100 jobs in metro

Software Quality Assurance Analysts in St. Louis, MO earn $142,660 median, with top earners (90th percentile) over $246,240. The lower cost of living here means the median translates to $158,511 of buying power versus an average-cost metro — better than the nominal number suggests.

$142,660
median
#7PharmacistHealthcare

Median $138,530 · 10th–90th $111,110$166,840 · 2,910 jobs in metro

Pharmacists in St. Louis, MO earn $138,530 median, with top earners (90th percentile) over $166,840. The lower cost of living here means the median translates to $153,922 of buying power versus an average-cost metro — better than the nominal number suggests.

$138,530
median
#8Marketing ManagerManagement

Median $137,900 · 10th–90th $80,740$231,700 · 3,540 jobs in metro

Marketing Managers in St. Louis, MO earn $137,900 median, with top earners (90th percentile) over $231,700. The lower cost of living here means the median translates to $153,222 of buying power versus an average-cost metro — better than the nominal number suggests.

$137,900
median

Median $136,120 · 10th–90th $77,620$170,960 · 1,260 jobs in metro

Physician Assistants in St. Louis, MO earn $136,120 median, with top earners (90th percentile) over $170,960. The lower cost of living here means the median translates to $151,244 of buying power versus an average-cost metro — better than the nominal number suggests.

$136,120
median
#10OptometristHealthcare

Median $135,090 · 10th–90th $71,500$193,430 · 340 jobs in metro

Optometrists in St. Louis, MO earn $135,090 median, with top earners (90th percentile) over $193,430. The lower cost of living here means the median translates to $150,100 of buying power versus an average-cost metro — better than the nominal number suggests.

$135,090
median

Full Ranking (64 Occupations)

RankRoleCategoryMedian10th–90thCOL-AdjustedJobs
1PediatricianHealthcare$223,910$65,700$344,020$248,789320
2DentistHealthcare$210,430$96,300$559,260$233,8111,250
3Computer and Information Systems ManagerTechnology$167,130$103,330$217,130$185,7006,160
4Financial ManagerFinance$158,780$92,720$304,260$176,4227,190
5LawyerLegal$142,690$67,600$306,650$158,5446,100
6Software Quality Assurance AnalystTechnology$142,660$79,000$246,240$158,511100
7PharmacistHealthcare$138,530$111,110$166,840$153,9222,910
8Marketing ManagerManagement$137,900$80,740$231,700$153,2223,540
9Physician AssistantHealthcare$136,120$77,620$170,960$151,2441,260
10OptometristHealthcare$135,090$71,500$193,430$150,100340
11Human Resources ManagerManagement$133,880$84,630$247,350$148,7561,940
12Nurse PractitionerHealthcare$131,580$108,340$164,280$146,2003,430
13Software DeveloperTechnology$129,030$77,730$169,030$143,3679,820
14Electrical EngineerEngineering$123,960$77,770$165,120$137,7331,290
15Sales ManagerManagement$123,870$64,370$243,000$137,6334,060
16VeterinarianHealthcare$122,460$74,680$195,480$136,067810
17Computer Occupations (Other)Technology$108,450$58,100$166,660$120,5007,330
18Information Security AnalystTechnology$106,420$65,330$166,900$118,2441,640
19Web DesignerTechnology$106,360$68,940$129,080$118,178490
20Medical and Health Services ManagerHealthcare$106,200$67,990$200,900$118,0005,000
21Database ArchitectTechnology$104,650$62,320$154,280$116,278550
22Engineers (Other)Engineering$103,880$62,900$155,130$115,422680
23Personal Financial AdvisorFinance$103,690$52,690$330,360$115,2112,630
24Computer Network ArchitectTechnology$103,370$62,080$170,730$114,8562,010
25Industrial EngineerEngineering$102,230$71,320$156,730$113,5892,580
26Business Professor (Postsecondary)Education$101,730$48,210$331,940$113,033910
27Management AnalystManagement$101,100$61,830$164,770$112,3335,100
28Physical TherapistHealthcare$100,600$77,390$124,190$111,7782,480
29Mechanical EngineerEngineering$100,340$65,900$149,060$111,4892,190
30Financial AnalystFinance$99,950$61,970$166,390$111,0562,650
31Data ScientistTechnology$99,600$59,500$158,310$110,6672,640
32AudiologistHealthcare$99,450$83,050$127,030$110,50090
33ArchitectEngineering$98,800$60,780$139,700$109,778880
34Dental HygienistHealthcare$97,650$78,760$99,400$108,5002,150
35Computer ProgrammerTechnology$96,920$63,230$132,120$107,689660
36Civil EngineerEngineering$96,830$67,510$140,460$107,5893,150
37Computer Systems AnalystTechnology$96,290$61,840$145,590$106,9893,920
38Occupational TherapistHealthcare$95,770$73,720$117,460$106,4111,860
39Software Quality Assurance TesterTechnology$94,590$59,600$169,820$105,1001,360
40General and Operations ManagerManagement$93,140$45,690$210,790$103,48946,410
41Network ArchitectTechnology$88,940$59,450$129,410$98,8222,840
42Speech-Language PathologistHealthcare$86,480$58,180$113,470$96,0891,630
43Registered NurseHealthcare$83,180$63,440$104,460$92,42235,200
44StatisticianTechnology$80,950$56,010$132,760$89,9440
45Financial ExaminerFinance$80,430$55,370$153,980$89,367850
46AccountantFinance$78,880$51,040$130,340$87,64413,610
47ElectricianTrades$77,170$46,890$104,800$85,7445,920
48PlumberTrades$77,000$47,040$121,230$85,5564,060
49Family Medicine PhysicianHealthcare$76,830$70,100$428,550$85,3671,660
50Computer Network Support SpecialistTechnology$75,060$46,390$131,610$83,4002,080
51Web DeveloperTechnology$74,780$48,310$136,380$83,089650
52Loan OfficerFinance$74,510$38,370$149,000$82,7892,690
53Market Research AnalystManagement$74,130$39,520$133,140$82,3676,980
54CarpenterTrades$70,990$45,000$99,550$78,8787,210
55Public Relations SpecialistCreative$65,170$43,640$107,990$72,4111,990
56Operations Research AnalystTechnology$63,650$49,180$125,800$70,722900
57Secondary School TeacherEducation$62,130$47,630$98,540$69,0339,870
58ParalegalLegal$61,970$45,950$97,830$68,8564,030
59Clinical Laboratory TechnologistHealthcare$61,830$38,400$96,860$68,7003,960
60Graphic DesignerCreative$61,000$39,930$88,740$67,7782,010
61Elementary School TeacherEducation$60,650$47,210$83,750$67,38913,440
62Automotive TechnicianTrades$58,190$36,280$78,140$64,6567,590
63Writer/AuthorCreative$57,390$45,380$100,350$63,767300
64WelderTrades$51,640$38,770$72,140$57,3782,820

Why These Roles Pay the Most in St. Louis, MO

St. Louis, MO's pay distribution reflects its mix of regional employers and industries, plus the local cost of living that affects nominal salary levels in the BLS data.

An average median salary above $90K places this metro in the top tier of U.S. cities for nominal pay. Most of that premium accrues to the upper percentiles of skilled and managerial occupations; entry-level and service-sector pay is closer to national norms.

St. Louis, MO's cost-of-living index of 90 runs 10% below the U.S. national average. Lower nominal pay here often translates to comparable or better purchasing power than higher headline numbers in coastal hubs — see the COL-Adjusted column for the apples-to-apples figure.

How to Use This Ranking

For salary negotiation, the median is a starting anchor — not the ceiling. A Pediatrician with five-plus years of experience in St. Louis, MO should be benchmarking against the 75th percentile ($283,965) or 90th percentile ($344,020), not the $223,910 median. Use the salary percentile calculator to place any specific salary into the BLS distribution for any role-and-city pair.

For cross-city comparisons, ignore the nominal Median column and look at COL-Adjusted. A $224K Pediatrician salary in St. Louis, MO (COL 90) translates to $249K of buying power in an average-cost metro — that is the apples-to-apples figure when weighing a relocation. Read the methodology behind these adjustments in our methodology page.

For job hunting, focus on the top-10 ranking above and on the role-by-role detail pages — each links through to a Pediatrician in St. Louis, MO page with full percentile breakdowns, year-over-year change, and prevailing-wage references for H-1B / PERM applicants.

Frequently Asked Questions

The highest paying job in St. Louis, MO is Pediatrician with a median salary of $223,910 and a 90th-percentile reading of $344,020. The role employs roughly 320 workers in this metro according to the Bureau of Labor Statistics' 2025 OEWS data.

29 of the 64 BLS-tracked occupations in St. Louis, MO have a median salary of $100,000 or higher. That is well above what most U.S. metros offer. See the full list ranked by median salary above.

Across 64 BLS-tracked occupations, the average median salary in St. Louis, MO is $101,234. The cost-of-living index is 90, so adjusted to a national-average baseline, the average is $112,482 in equivalent purchasing power.

St. Louis, MO has a cost-of-living index of 90, below the national average. Nominal pay translates better than face value, making it a strong choice for many careers — particularly the Pediatrician, Dentist, Computer and Information Systems Manager occupations at the top of the ranking.

Every wage figure on this page is sourced from the U.S. Bureau of Labor Statistics' Occupational Employment and Wage Statistics (OEWS) program at bls.gov/oes — public domain federal survey data covering about 1.2 million U.S. employers across all industries. The OEWS publishes 10th, 25th, 50th (median), 75th, and 90th percentile wages by Metropolitan Statistical Area and Standard Occupational Classification (SOC) code. The same data is used by the Department of Labor for prevailing wage determinations.

Sources: Bureau of Labor Statistics OEWS
Last updated:

Rankings based on BLS Occupational Employment and Wage Statistics, 2025 reference period. COL adjustments use a composite cost-of-living index calibrated to U.S. average = 100.

Source: BLS Occupational Employment and Wage Statistics, 2026.