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Updated May 2026 · BLS OEWS 2025

Clinical Laboratory Technologist Salary in San Diego, CA

Healthcare · SOC 29-2010 · COL Index 160.2

Clinical Laboratory Technologists in San Diego, CA earn a median salary of $63,770 as of 2025, with a 10th-to-90th percentile range of $45,130 to $127,710. The mean is $73,640 across approximately 2,740 workers. Adjusted for San Diego, CA's cost-of-living index of 160.2, the median equates to $39,806 of purchasing power in an average-cost U.S. metro.

Clinical Laboratory Technologist pay in San Diego, CA runs close to the national median: $63,770 locally versus $63,789 nationally. Cities with national-market wages typically have moderate cost-of-living and balanced labor supply-and-demand.

Cost-of-living in San Diego, CA runs at index 160.2 — well above the national 100 baseline. Adjusted for cost-of-living, the $63,770 median translates to roughly $39,806 in national-baseline dollars, a useful framing for relocation decisions. Wage distribution at the 25th, 50th, 75th, and 90th percentiles: $52,586, $63,770, $95,740, $127,710. 2,740 Clinical Laboratory Technologist workers are documented in San Diego, CA per the BLS OEWS survey. The percentile spread is the most useful framing — entry-level pay clusters near p25, mid-career near p50, senior-level near p75-p90.

$63,770
Median Salary
$73,640
Mean Salary
$39,806
COL-Adjusted
2,740
Employment

Salary Distribution

Percentile Breakdown

PercentileSalaryCOL-Adjusted
10th Percentile (Entry Level)$45,130$28,171
25th Percentile$52,586$32,825
50th Percentile (Median)$63,770$39,806
75th Percentile$95,740$59,763
90th Percentile (Top Earners)$127,710$79,719

What These Numbers Tell You

The spread between the 10th and 90th percentile for Clinical Laboratory Technologists in San Diego, CA is unusually wide — top earners take home roughly 2.8× what the bottom decile earns. That signals a long career ladder: substantial pay gains accrue with seniority, specialization, and movement to larger employers. Workers entering this role should expect to start near the 25th percentile and target the median by year three to five.

San Diego, CA's cost-of-living index of 160.2 means $63,770 here has the same purchasing power as $39,806 in an average-cost U.S. metro. Housing dominates the gap; in markets at this level, mortgage or rent typically consumes 35–45% of pre-tax pay even at the median, which is why nominal salary numbers materially overstate take-home value.

San Diego, CA ranks #24 of 70 BLS-tracked metros for Clinical Laboratory Technologist pay — in the upper half (34th percentile of metros) but not the top tier.

How to Use This in Negotiation

The classic negotiation move is to anchor your ask on the 75th percentile of the BLS band — $95,740 for Clinical Laboratory Technologists in San Diego, CA — when you have meaningful experience, then bring evidence (years on the job, scope of past work, relevant certifications, comparable offers) to justify why you sit at that point in the distribution. Anchoring on the median when you have 5+ years of experience leaves money on the table; anchoring on the 90th percentile ($127,710) without strong evidence undercuts credibility.

For new entrants, the 25th-to-50th percentile band ($52,586$63,770) is the realistic target. For mid-career workers, the median-to-75th band ($63,770$95,740) is the right anchor. Senior specialists and managers should be benchmarking against the 75th-to-90th band ($95,740$127,710).

For specific scripts and a full negotiation framework, see the data-driven salary negotiation guide. To benchmark your current pay, the salary percentile calculator places any number into the BLS distribution for this role and metro.

How This Salary Is Calculated

Wage figures come from the U.S. Bureau of Labor Statistics' Occupational Employment and Wage Statistics (OEWS) program — a federal survey of about 1.2 million U.S. establishments, published once per year by Metropolitan Statistical Area (MSA) and Standard Occupational Classification (SOC) code. The San Diego, CA percentile bands above (10th, 25th, 50th, 75th, 90th) and the mean are pulled directly from the BLS data file for SOC code 29-2010 in this MSA. The COL-adjusted figure rebases salary to a U.S. national average COL of 100, using a composite index derived from public housing, food, and transportation data. Read the full methodology for details.

Frequently Asked Questions

What is the average Clinical Laboratory Technologist salary in San Diego, CA?

Clinical Laboratory Technologists in San Diego, CA earn a median salary of $63,770 as of 2025, based on Bureau of Labor Statistics OEWS data. The mean (employment-weighted average) is $73,640 across roughly 2,740 workers in this metro.

What is the salary range for Clinical Laboratory Technologists in San Diego, CA?

Pay ranges from $45,130 at the 10th percentile to $127,710 at the 90th percentile — a $82,580 spread. The 25th-to-75th percentile band ($52,586 to $95,740) is the typical anchor for salary negotiation.

Is $63,770 a good Clinical Laboratory Technologist salary in San Diego, CA?

$63,770 is the BLS median — half of Clinical Laboratory Technologists in San Diego, CA earn more, half earn less. Whether it is "good" depends on your experience: new entrants typically land near the 25th percentile ($52,586), mid-career workers near the median, and senior specialists near or above the 75th percentile ($95,740). Cost-of-living-adjusted to a national average baseline, the median equates to $39,806.

How does Clinical Laboratory Technologist pay in San Diego, CA compare to other metros?

San Diego, CA ranks #24 of 70 BLS-tracked metros for Clinical Laboratory Technologist median pay. It sits in the upper half but not the top tier.

Where does this Clinical Laboratory Technologist salary data come from?

Every wage figure comes from the U.S. Bureau of Labor Statistics' Occupational Employment and Wage Statistics (OEWS) program at bls.gov/oes — public domain federal data covering 1.2 million U.S. employers. The same data feeds the U.S. Department of Labor's prevailing wage system used for H-1B and federal contracting wage determinations.

Source: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics, San Diego, CA MSA, SOC 29-2010, 2025 release. Public domain. See bls.gov/oes. Cite as: "SalaryTruth, BLS OEWS 2025."

Last refreshed 2026-05-21 · 2,740 Clinical Laboratory Technologists tracked in San Diego, CA.