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Updated May 2026 · BLS OEWS 2025

Physician Assistant Salary in San Antonio, TX

Healthcare · SOC 29-1071 · COL Index 91.5

Physician Assistants in San Antonio, TX earn a median salary of $140,160 as of 2025, with a 10th-to-90th percentile range of $113,840 to $201,640. The mean is $144,100 across approximately 650 workers. Adjusted for San Antonio, TX's cost-of-living index of 91.5, the median equates to $153,180 of purchasing power in an average-cost U.S. metro.

Physician Assistant pay in San Antonio, TX runs close to the national median: $140,160 locally versus $138,339 nationally. Cities with national-market wages typically have moderate cost-of-living and balanced labor supply-and-demand.

Cost-of-living in San Antonio, TX runs below the national baseline (index 91.5). The cost-adjusted purchasing power of $140,160 works out to roughly $153,180 in national-baseline dollars — often higher real income than in high-cost coastal cities at the same gross wage. Wage distribution at the 25th, 50th, 75th, and 90th percentiles: $124,368, $140,160, $170,900, $201,640. 650 Physician Assistant workers are documented in San Antonio, TX per the BLS OEWS survey. The percentile spread is the most useful framing — entry-level pay clusters near p25, mid-career near p50, senior-level near p75-p90.

$140,160
Median Salary
$144,100
Mean Salary
$153,180
COL-Adjusted
650
Employment

Salary Distribution

Percentile Breakdown

PercentileSalaryCOL-Adjusted
10th Percentile (Entry Level)$113,840$124,415
25th Percentile$124,368$135,921
50th Percentile (Median)$140,160$153,180
75th Percentile$170,900$186,776
90th Percentile (Top Earners)$201,640$220,372

What These Numbers Tell You

The 10th-to-90th percentile spread for Physician Assistants in San Antonio, TX is relatively tight (1.8×), suggesting pay is largely standardized — most workers earn within a fairly narrow band of the median $140,160. Roles with this distribution tend to have less negotiation leverage at the top end, but also less risk of underpayment at the bottom.

San Antonio, TX's cost-of-living index of 91.5 runs below the U.S. average, so a $140,160 salary here has the equivalent purchasing power of about $153,180 in an average-cost metro. Lower nominal pay in markets like this often translates to comparable or better real income than higher headline numbers in coastal hubs.

San Antonio, TX ranks #18 of 70 BLS-tracked metros for Physician Assistant pay — in the upper half (26th percentile of metros) but not the top tier.

How to Use This in Negotiation

The classic negotiation move is to anchor your ask on the 75th percentile of the BLS band — $170,900 for Physician Assistants in San Antonio, TX — when you have meaningful experience, then bring evidence (years on the job, scope of past work, relevant certifications, comparable offers) to justify why you sit at that point in the distribution. Anchoring on the median when you have 5+ years of experience leaves money on the table; anchoring on the 90th percentile ($201,640) without strong evidence undercuts credibility.

For new entrants, the 25th-to-50th percentile band ($124,368$140,160) is the realistic target. For mid-career workers, the median-to-75th band ($140,160$170,900) is the right anchor. Senior specialists and managers should be benchmarking against the 75th-to-90th band ($170,900$201,640).

For specific scripts and a full negotiation framework, see the data-driven salary negotiation guide. To benchmark your current pay, the salary percentile calculator places any number into the BLS distribution for this role and metro.

How This Salary Is Calculated

Wage figures come from the U.S. Bureau of Labor Statistics' Occupational Employment and Wage Statistics (OEWS) program — a federal survey of about 1.2 million U.S. establishments, published once per year by Metropolitan Statistical Area (MSA) and Standard Occupational Classification (SOC) code. The San Antonio, TX percentile bands above (10th, 25th, 50th, 75th, 90th) and the mean are pulled directly from the BLS data file for SOC code 29-1071 in this MSA. The COL-adjusted figure rebases salary to a U.S. national average COL of 100, using a composite index derived from public housing, food, and transportation data. Read the full methodology for details.

Frequently Asked Questions

What is the average Physician Assistant salary in San Antonio, TX?

Physician Assistants in San Antonio, TX earn a median salary of $140,160 as of 2025, based on Bureau of Labor Statistics OEWS data. The mean (employment-weighted average) is $144,100 across roughly 650 workers in this metro.

What is the salary range for Physician Assistants in San Antonio, TX?

Pay ranges from $113,840 at the 10th percentile to $201,640 at the 90th percentile — a $87,800 spread. The 25th-to-75th percentile band ($124,368 to $170,900) is the typical anchor for salary negotiation.

Is $140,160 a good Physician Assistant salary in San Antonio, TX?

$140,160 is the BLS median — half of Physician Assistants in San Antonio, TX earn more, half earn less. Whether it is "good" depends on your experience: new entrants typically land near the 25th percentile ($124,368), mid-career workers near the median, and senior specialists near or above the 75th percentile ($170,900). Cost-of-living-adjusted to a national average baseline, the median equates to $153,180.

How does Physician Assistant pay in San Antonio, TX compare to other metros?

San Antonio, TX ranks #18 of 70 BLS-tracked metros for Physician Assistant median pay. It sits in the upper half but not the top tier.

Where does this Physician Assistant salary data come from?

Every wage figure comes from the U.S. Bureau of Labor Statistics' Occupational Employment and Wage Statistics (OEWS) program at bls.gov/oes — public domain federal data covering 1.2 million U.S. employers. The same data feeds the U.S. Department of Labor's prevailing wage system used for H-1B and federal contracting wage determinations.

Source: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics, San Antonio, TX MSA, SOC 29-1071, 2025 release. Public domain. See bls.gov/oes. Cite as: "SalaryTruth, BLS OEWS 2025."

Last refreshed 2026-05-21 · 650 Physician Assistants tracked in San Antonio, TX.