Updated May 2026 · BLS OEWS 2025
Clinical Laboratory Technologist Salary in Buffalo, NY
Healthcare · SOC 29-2010 · COL Index 92.5
Clinical Laboratory Technologists in Buffalo, NY earn a median salary of $78,050 as of 2025, with a 10th-to-90th percentile range of $48,370 to $104,110. The mean is $76,120 across approximately 710 workers. Adjusted for Buffalo, NY's cost-of-living index of 92.5, the median equates to $84,378 of purchasing power in an average-cost U.S. metro.
Clinical Laboratory Technologist in Buffalo, NY pays a substantial premium over the national median: $78,050 versus $63,789 nationally, roughly 22% above. The premium reflects local labor demand, cost-of-living adjustment, and industry concentration.
Cost-of-living in Buffalo, NY runs below the national baseline (index 92.5). The cost-adjusted purchasing power of $78,050 works out to roughly $84,378 in national-baseline dollars — often higher real income than in high-cost coastal cities at the same gross wage. Wage distribution at the 25th, 50th, 75th, and 90th percentiles: $60,242, $78,050, $91,080, $104,110. 710 Clinical Laboratory Technologist workers are documented in Buffalo, NY per the BLS OEWS survey. The percentile spread is the most useful framing — entry-level pay clusters near p25, mid-career near p50, senior-level near p75-p90.
Salary Distribution
Percentile Breakdown
| Percentile | Salary | COL-Adjusted |
|---|---|---|
| 10th Percentile (Entry Level) | $48,370 | $52,292 |
| 25th Percentile | $60,242 | $65,126 |
| 50th Percentile (Median) | $78,050 | $84,378 |
| 75th Percentile | $91,080 | $98,465 |
| 90th Percentile (Top Earners) | $104,110 | $112,551 |
What These Numbers Tell You
The 10th-to-90th percentile band for Clinical Laboratory Technologists in Buffalo, NY is moderately wide — the 90th-percentile worker earns about 2.2× the 10th-percentile worker. That is typical for a professional role with standard career progression: experience, scope, and employer size all matter, but the spread is not so extreme that the role bifurcates into separate sub-markets.
Buffalo, NY's cost-of-living index of 92.5 runs below the U.S. average, so a $78,050 salary here has the equivalent purchasing power of about $84,378 in an average-cost metro. Lower nominal pay in markets like this often translates to comparable or better real income than higher headline numbers in coastal hubs.
Buffalo, NY ranks #10 of 70 BLS-tracked metros for Clinical Laboratory Technologist pay — in the top quartile nationally (top 14%). Markets in this band tend to be major regional employer hubs even when they are not the absolute highest-cost cities.
How to Use This in Negotiation
The classic negotiation move is to anchor your ask on the 75th percentile of the BLS band — $91,080 for Clinical Laboratory Technologists in Buffalo, NY — when you have meaningful experience, then bring evidence (years on the job, scope of past work, relevant certifications, comparable offers) to justify why you sit at that point in the distribution. Anchoring on the median when you have 5+ years of experience leaves money on the table; anchoring on the 90th percentile ($104,110) without strong evidence undercuts credibility.
For new entrants, the 25th-to-50th percentile band ($60,242–$78,050) is the realistic target. For mid-career workers, the median-to-75th band ($78,050–$91,080) is the right anchor. Senior specialists and managers should be benchmarking against the 75th-to-90th band ($91,080–$104,110).
For specific scripts and a full negotiation framework, see the data-driven salary negotiation guide. To benchmark your current pay, the salary percentile calculator places any number into the BLS distribution for this role and metro.
How This Salary Is Calculated
Wage figures come from the U.S. Bureau of Labor Statistics' Occupational Employment and Wage Statistics (OEWS) program — a federal survey of about 1.2 million U.S. establishments, published once per year by Metropolitan Statistical Area (MSA) and Standard Occupational Classification (SOC) code. The Buffalo, NY percentile bands above (10th, 25th, 50th, 75th, 90th) and the mean are pulled directly from the BLS data file for SOC code 29-2010 in this MSA. The COL-adjusted figure rebases salary to a U.S. national average COL of 100, using a composite index derived from public housing, food, and transportation data. Read the full methodology for details.
Frequently Asked Questions
What is the average Clinical Laboratory Technologist salary in Buffalo, NY?
Clinical Laboratory Technologists in Buffalo, NY earn a median salary of $78,050 as of 2025, based on Bureau of Labor Statistics OEWS data. The mean (employment-weighted average) is $76,120 across roughly 710 workers in this metro.
What is the salary range for Clinical Laboratory Technologists in Buffalo, NY?
Pay ranges from $48,370 at the 10th percentile to $104,110 at the 90th percentile — a $55,740 spread. The 25th-to-75th percentile band ($60,242 to $91,080) is the typical anchor for salary negotiation.
Is $78,050 a good Clinical Laboratory Technologist salary in Buffalo, NY?
$78,050 is the BLS median — half of Clinical Laboratory Technologists in Buffalo, NY earn more, half earn less. Whether it is "good" depends on your experience: new entrants typically land near the 25th percentile ($60,242), mid-career workers near the median, and senior specialists near or above the 75th percentile ($91,080). Cost-of-living-adjusted to a national average baseline, the median equates to $84,378.
How does Clinical Laboratory Technologist pay in Buffalo, NY compare to other metros?
Buffalo, NY ranks #10 of 70 BLS-tracked metros for Clinical Laboratory Technologist median pay. It sits in the top quartile of U.S. metros for this role.
Where does this Clinical Laboratory Technologist salary data come from?
Every wage figure comes from the U.S. Bureau of Labor Statistics' Occupational Employment and Wage Statistics (OEWS) program at bls.gov/oes — public domain federal data covering 1.2 million U.S. employers. The same data feeds the U.S. Department of Labor's prevailing wage system used for H-1B and federal contracting wage determinations.
Source: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics, Buffalo, NY MSA, SOC 29-2010, 2025 release. Public domain. See bls.gov/oes. Cite as: "SalaryTruth, BLS OEWS 2025."
Last refreshed 2026-05-21 · 710 Clinical Laboratory Technologists tracked in Buffalo, NY.